In treating Lyme disease, which antibiotic is preferred for use in children or pregnant women?

Amoxicillin is the preferred antibiotic for treating Lyme disease in children and pregnant women primarily due to its safety profile and effectiveness against the causal agent, Borrelia burgdorferi.

In both pediatric and pregnant populations, the choice of antibiotics needs to prioritize safety, as certain medications, such as doxycycline, are contraindicated in young children and pregnant women due to the risk of tooth discoloration and other potential side effects. In contrast, amoxicillin has a well-established safety record in these groups and is effective in treating early Lyme disease, making it the go-to option.

Cefuroxime, while also effective against Lyme disease, is not as commonly utilized in children and pregnant women as amoxicillin due to its broader spectrum of possible side effects and lesser familiarity in these populations. Azithromycin, though effective for certain infections, is not the first-line treatment for Lyme disease. Thus, amoxicillin is favored for its proven efficacy and safety in these specific patient groups.