In which geographical regions is Lyme disease most prevalent?

The correct choice emphasizes that Lyme disease is most prevalent in wooded and grassy areas. This is due to the ecological niche in which the primary vectors (ticks, particularly the black-legged tick, also known as the deer tick) thrive. These ticks are commonly found in environments where there is ample vegetation and wildlife, especially in areas where deer and small mammals—hosts for the ticks—are present.

In such habitats, the combination of humidity, temperature, and the presence of host animals creates ideal conditions for ticks to flourish and, consequently, increase the likelihood of Lyme disease transmission to humans. Areas that are densely forested, mixed woodlands, and regions with tall grasses provide both the habitat for ticks and the opportunity for human interaction, particularly during outdoor activities such as hiking, camping, and gardening.

Other geographical regions mentioned, such as deserts, tropical regions, and urban environments, do not provide the conducive conditions needed for the survival and reproduction of the ticks that transmit Lyme disease. Deserts lack sufficient moisture and host animal populations, tropical regions may contain different pathogens more suited to their environment, and urban environments often have limited natural habitats that support tick populations.