What is the drug of choice for the treatment of pneumocystis jiroveci?

Study for the Infectious Disease Test. Prepare with flashcards, multiple choice questions, hints, and explanations. Get ready for your exam!

The drug of choice for the treatment of Pneumocystis jiroveci pneumonia (PCP) is trimethoprim-sulfamethoxazole, commonly known as Bactrim. This antibiotic combination is effective against Pneumocystis jiroveci, which is a fungus that often affects immunocompromised individuals, such as those with HIV/AIDS.

Bactrim works by inhibiting folic acid synthesis in the organism, which is essential for its growth and replication. The efficacy of this drug in treating PCP is well-documented, and it can also be used as prophylaxis in patients at high risk for developing the infection. The regimen is typically continued until there is an improvement in the patient's clinical condition, as well as a resolution of the symptoms associated with the pneumonia.

Other options listed do not target Pneumocystis jiroveci effectively. Doxycycline is primarily used for bacterial infections, and it would not be appropriate for treating a fungal infection like PCP. Isoniazid is an antituberculous medication, specifically aimed at treating tuberculosis, and does not have action against Pneumocystis jiroveci. Ganciclovir is an antiviral medication used mainly for cytomegal

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