Which of the following is commonly used in the acute treatment of a diabetic foot infection?

Clindamycin is commonly used in the acute treatment of a diabetic foot infection due to its excellent coverage against Gram-positive bacteria, including Streptococcus and Staphylococcus species, which are often involved in such infections. Additionally, it provides good coverage against anaerobic bacteria, which can also be present in diabetic foot infections. This makes clindamycin a suitable choice, especially when considering the polymicrobial nature of these infections.

The choice of clindamycin is further supported in cases where there is a need to avoid certain side effects or the development of resistance associated with other antibiotics. It is also effective for patients who may have penicillin allergies, as clindamycin can serve as an alternative treatment. In diabetic foot infections, where the risk of developing serious complications is high, choosing an antibiotic with this wide spectrum of activity is critical for effective management.