Which organism has been linked to reactive arthritis?

Reactive arthritis is an inflammatory joint condition that can develop in response to an infection elsewhere in the body. Shigella, particularly, has been identified as one of the notable organisms associated with reactive arthritis. This gastrointestinal infection, caused by Shigella bacteria, can trigger an autoimmune response in some individuals, leading to the development of arthritis after the resolution of the acute infection. Inflammation occurs as the body's immune system continues to react, not just to the pathogen itself but also due to the results of the infection.

Other organisms, such as Salmonella and Campylobacter, have also been linked to reactive arthritis, but Shigella is particularly noted for its strong association. E. coli is generally less documented in this context. Understanding these connections can help healthcare providers anticipate and manage potential complications in patients who have experienced gastrointestinal infections.